miR-23a Promotes the Transition from Indolent to Invasive Colorectal Cancer
نویسندگان
چکیده
منابع مشابه
miR-23a promotes the transition from indolent to invasive colorectal cancer.
Colorectal cancer is a classic example of a tumor that progresses through multiple distinct stages in its evolution. To understand the mechanisms regulating the transition from indolent to invasive disease, we profiled somatic copy number alterations in noninvasive adenomas and invasive adenocarcinomas from Apc and DNA mismatch repair (MMR) mutant mouse models. We identified a recurrent amplico...
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ژورنال
عنوان ژورنال: Cancer Discovery
سال: 2012
ISSN: 2159-8274,2159-8290
DOI: 10.1158/2159-8290.cd-11-0267